Antimicrobial resistance has evolved to become a worldwide health threat. According to the RAND EUROPE reports, drug-resistant superbugs will kill more people than cancer and cost up to $100 trillion by 2050. Bacteria that cause nosocomial infection including Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae are classified by WHO as the priority 1 pathogens which new drugs are most urgently needed.
Vaccination is the most effective strategy to prevent infectious diseases.
The COVID-19 pandemics reminds us that life is unpredictable. New diseases and accidents may happen suddenly. Vaccination with A. baumannii vaccine may protect individuals from the nosocomial infections or at least to reduce the disease severity when hospitalized.