Point-of-Care Diagnostic Assays Using Novel Electrical Microfluidic Chips

Project Description
This work presents a novel handheld analyzer with disposable lab-on-a-chip technology for the electrical detection of the anesthetic propofol in human plasma samples for clinical diagnoses. The developed on-chip biosensors are based on the conduction of molecularly imprinted polymers (MIPs) that employ label-free electrical detection techniques.

Intellectual Property

1. Method for fabricating microfluidic structures, (US 9682374B2)

2. Microfluidic device with fluid driving capability (US 8651451B2)

3. Microfluidic chip device and method of making the same (JP 5379766)


Key Publications
Chien-Chong Hong*, Chie-Pein Chen*, Jia-Cherng Horng, and Szu-Yig Chen, “Point-of-Care Protein Sensing Platform based on Immuno-Like Membrane with Molecularly-Aligned Nanocavities,” Biosensors & Bioelectronics, 2013, 50, 425-430.

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